Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH) : The Quintessential Moonlighting Protein in Normal Cell Function and in Human Disease

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Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH): The Quintessential Moonlighting Protein in Normal Cell Function and in Human Disease examines the biochemical protein interactions of the multi-dimensional protein GAPDH, further considering the regulatory mechanisms through which cells control their functional diversity. This proteins diverse activities range from nuclear tRNA export and the maintenance of genomic integrity, to cytoplasmic post-transcriptional control of gene expression and receptor mediated cell signaling, to membrane facilitation of iron metabolism, trafficking and fusion. This book will be of great interest to basic scientists, clinicians and students, including molecular and cell biologists, immunologists, pathologists and clinical researchers who are interested in the biochemistry of GAPDH in health and disease.
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Product details

Author: Michael A. Sirover

Format: Paperback | 324 pages

Dimensions:152 x 229 x 5.08mm | 520g

Publication Date: 25 May 2017

Publisher: Elsevier Science Publishing Co Inc

Language: English

ISBN 10: 012809852X

ISBN 13: 9780128098523